EGFR COPY NUMBER VARIATION Detail (hg38) (EGFR)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr7:55,086,794-55,279,321 View the variant detail on this assembly version. |
hg38 | chr7:55,019,101-55,211,628 |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
---|---|---|---|---|---|---|---|---|---|
head and neck squamous cell carcinoma | B |
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Poor Outcome | Somatic | 4 | 17538160 | Detail | |
lung non-small cell carcinoma | Erlotinib,Gefitinib | B |
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Sensitivity/Response | Somatic | 4 | 20826716 | Detail |
lung non-small cell carcinoma | Gefitinib,Erlotinib | B |
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Sensitivity/Response | Somatic | 4 | 27664271 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
In 134 patients with head and neck squamous cancer 32 had copy number variations. Tumors with variat... | CIViC Evidence | Detail |
The result of the analysis found that EGFR gene copy number was associated with increased OS and PFS... | CIViC Evidence | Detail |
Among TKI-treated patients, increased EGFR gene copy number appears to be associated with improved s... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- EGFR
- Genome
- hg38
- Position
- chr7:55,019,101-55,211,628
- Variant Type
- cnv
- Variant (CIViC) (CIViC Variant)
- COPY NUMBER VARIATION
- Transcript 1 (CIViC Variant)
- ENST00000275493.2
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/191
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